The Pakistani market for pancreatic and bile duct cancer drugs is poised for growth, driven by rising cancer prevalence and improving healthcare infrastructure. Increasing awareness campaigns and government support for cancer management initiatives are key contributors. The expanding pharmaceutical sector and international partnerships are facilitating access to innovative therapies. Challenges such as limited healthcare resources are being addressed through policy reforms and investments in diagnostic facilities. The focus on expanding treatment options and clinical research is expected to accelerate market growth, making Pakistan an emerging hub for pancreatic and bile duct cancer therapeutics in the region.
Pakistan Pancreatic And Bile Duct Cancer Market characteristics
Note that data for 2020 only included data from January to March; price per gram is in US $. Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables. M&A activities help companies expand capabilities, market reach, and competitive positioning.
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First, we designed and implemented an anonymous marketplace data collection and analysis pipeline to gather and identify opioids data in 16 anonymous marketplaces and forums over a period of almost 9 years between 2011 and 2020. Second, we fine-tuned the semantic comparison model proposed by Yuan et al [19] for opioid jargon detection, which can recognize the opioid jargon as innocent-looking terms and the dedicated terms only used in the anonymous marketplaces and forums. In this way, we generated a rich underground marketplace opioid vocabulary of 311 opioid keywords with 13 categories.
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- We will never announce emergency procedures through forums, Telegram, or other third-party channels.
- The results provide insight into opioid trading in the anonymous markets and forums and may prove an effective mitigation data point for illuminating the opioid supply chain.
- This onion is protected by custom sophisticated CAPTCHA systems and POWenabled to give you the best experience using DrugHub market.
- The rising prevalence of risk factors such as smoking and obesity contributes to higher cancer incidence.
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- Administered by seasoned experts, pen-tested by top security specialists,with industry-leading protections like END GAME DDoS filter.
- The life sciences industry continues to pour manufacturing investments into the state.
- Drug Hub operates a private Jabber server for push notifications and optional vendor communication.
- Europol said that 288 suspects were arrested and more than 50.8 million euros ($53.4 million) in cash and virtual currencies, 850 kilograms of drugs and 117 firearms were seized in a series of raids in several countries.
The drugmaker followed that up with a $2 billion deal in September for manufacturing space at Fujifilm Biotechnologies’ Holly Springs location. It also recently announced plans to build a second multibillion-dollar facility in Wilson. Speculation abounds that DrugHub’s servers may have already been compromised by law enforcement. If true, this would not only spell disaster for the platform’s users but also serve as a stark reminder of the stakes involved in operating within this clandestine realm. In this way, we collected 7100 promotion posts and 6408 review posts from forum posts in total.
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This paper seeks to complement current studies widening the understanding of opioid supply chains in underground marketplaces using comprehensive, large-scale, longitudinal anonymous marketplace and forum data. To this end, we propose a series of techniques to collect data; identify opioid jargon terms used in the anonymous marketplaces and forums; and profile the opioid commodities, suppliers, and transactions. Specifically, we first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. Subsequently, we conducted a comprehensive, large-scale, longitudinal study to demystify opioid trading activities in anonymous markets and forums. In total, we collected 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums. As observed in our data set, the top 3 marketplaces with the most opioid listings are Agora, Evolution, and Apollon.
Pakistan Pancreatic And Bile Duct Cancer Drug Market Growth Forecast
To identify forum posts related to opioid commodity promotion and review, our methodology was designed to filter forum posts with opioid keywords and then use a classifier to the posts with the topics of interest. The classifier was built upon transfer learning and a crafted objective function that heavily weighs the penalty of misclassifying a positive instance. Phishing sites with similar addresses are common in the darknet ecosystem.
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Novartis plans to build two new radioligand therapy manufacturing facilities in Florida and Texas, and in October, the U.K.’s AstraZeneca opened an expanded manufacturing facility in Coppell to double the production of its high blood potassium treatment, Lokelma. Like any marketplace, branding is key, even in the shadowy corners of the internet. But this logo, created using Adobe Illustrator version 24.0—a software outdated as of 2019—became the first crack in DrugHub’s armor. Embedded within the logo’s metadata was a treasure trove of information for anyone skilled in Open Source Intelligence (OSINT). The use of outdated software was not just a cosmetic flaw; it signaled a broader negligence in keeping up with technological advancements. Danny has worked in technology communications for more than 20 years, and has been writing about developments the longevity sector since 2019.
DrugHub Market Official Review
- The classifier was built upon transfer learning and a crafted objective function that heavily weighs the penalty of misclassifying a positive instance.
- In fact, the shutdown of the marketplace Evolution was discovered to be an exit scam, with the site’s operators shutting down abruptly to steal the approximately US $12 million in bitcoins that it was holding as an escrow [39].
- We found evidence through extensive analyses of the anonymous online market of pervasive supply, which fuels the international opioid epidemic.
- Established through the merger of G42 Healthcare and Mubadala Health, M42 is fast-becoming a major player in global healthcare.
- Novartis plans to build two new radioligand therapy manufacturing facilities in Florida and Texas, and in October, the U.K.’s AstraZeneca opened an expanded manufacturing facility in Coppell to double the production of its high blood potassium treatment, Lokelma.
The results provide insight into opioid trading in the anonymous markets and forums and may prove an effective mitigation data point for illuminating the opioid supply chain. DrugHub Market is the #1 darknetmarketplace launched in August 2023 by the legendary team behind WhiteHouse Market. Now over 3 years strong, DrugHub boasts 100,000+ listings, over 500,000users, and more than 4,000 verifiedvendors. We are the premier platform for secure, private, Monero(XMR)-only transactions, with industry-leading security and uptime. This finding is roughly in line with the observation of 57 opioid vendors’ origin in a marketplace named Cryptomarket during the period of October 2015 through April 2016, which was reported by Duxbury et al [6].
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When the purchase is made, the opioid trader ships the purchased item to the buyer (step 10). Once the item is received, the buyer finalizes the purchase by notifying the anonymous online marketplace to release the funds held in escrow (step 11) [8,9]. After that, an opioid buyer often leaves review comments under the product listing or discusses the purchasing experience in the forum (step 12). The Vietnamese market for pancreatic and bile duct cancer drugs is projected to grow steadily over the next five years, driven by increasing healthcare investments and rising awareness about early diagnosis. The expanding pharmaceutical sector and government initiatives to improve cancer care infrastructure are crucial factors. Additionally, the growing prevalence of these cancers among the aging population is expected to boost demand for advanced therapeutics.
Data Collection
DrugHub’s origins trace back to the remnants of White House Market and its eventual merger with Supermarket. The platform’s creators, likely seasoned veterans of the darknet ecosystem, should have known better than to leave such glaring vulnerabilities. Yet, these oversights suggest a departure from the meticulous operational security (OPSEC) practices that once defined successful darknet marketplaces. The decision to operate clearnet mirrors alongside Tor-hidden services compounded the problem. While clearnet mirrors can provide redundancy and accessibility, they also expose the platform to the scrutiny of law enforcement agencies. In DrugHub’s case, the risks were amplified by its server’s geographical location and its choice of hosting providers.
Drug Hub features a unique mirror distribution system where each user receives personal mirror links. Unlike traditional marketplaces with shared backup mirrors, our system provides truly unique onion addresses for enhanced security and reliability. Become part of the #1 darknet marketplace trusted by over 500,000 users and 100k+ listings.
North America continues to dominate the market, supported by a robust technological ecosystem, early adoption of advanced solutions, and sustained investments in innovation and automation. Europe follows closely, driven by stringent regulatory standards, strong sustainability initiatives, and ongoing modernization across industrial and commercial sectors. The Asia-Pacific region is projected to register the fastest growth, propelled by rapid industrialization, expanding manufacturing capacity, urban development, and increasing uptake of cost-effective technologies across China, India, and Southeast Asian economies. Latin America offers emerging growth potential through infrastructure expansion and rising industrial activity, while the Middle East & Africa benefits from growing investments in energy, construction, and smart infrastructure projects. Collectively, regional diversification, supportive policy frameworks, and expanding end-use applications are generating substantial growth opportunities for the global Pancreatic And Bile Duct Cancer Drug Market.
- In addition, we set parameters such as sleeping time to limit the speed of crawling.
- This ensures secure, encrypted communication with verification of staff identity.
- However, to the best of our knowledge, no large-scale study, which may cross multiple anonymous marketplaces and is cross-sectional, has been conducted to profile the opioid supply chain and unveil characteristics of opioid suppliers, commodities, and transactions.
- The metadata revealed not only the tools used but hinted at the environment in which the logo was crafted.
- Hence, every word has 2 vectors, each describing the word’s relations with other words in one corpus.
- Like any marketplace, branding is key, even in the shadowy corners of the internet.
- Customers pay a standard 5% commission that can be adjusted based on account activity and volume.
- Owing to the anonymity of the underground marketplaces and forums, there exists no ground truth to link users with their IDs.
- On your first visit, save the market’s PGP key so you can verify the legitimacy of any mirror provided.
Indonesia’s pancreatic and bile duct cancer drug market is anticipated to expand rapidly, driven by increasing disease awareness and a burgeoning healthcare sector. Government initiatives aimed at improving cancer screening and treatment infrastructure are pivotal. The rising prevalence of risk factors such as smoking and obesity contributes to higher cancer incidence. Market growth is further supported by international collaborations and investments in healthcare technology. The focus on improving access to innovative therapies and expanding clinical research activities positions Indonesia as a promising emerging market for pancreatic and bile duct cancer treatments. The market for pancreatic and bile duct cancer drugs in Bangladesh is set to expand, driven by increasing disease prevalence and ongoing healthcare reforms.
Law enforcement agencies around the world seized an online marketplace and arrested nearly 300 people allegedly involved in buying and selling drugs, European Union law enforcement agency Europol said Tuesday. Minister of Health Sylvia Jones has said the government plans to open 19 of the treatment hubs and 375 highly supportive housing units at a planned cost of $378 million. The hubs will not provide a safe supply of illicit drugs, supervised consumption services or needle exchange programs. HUB Organoids (HUB) is the global leader in the field of adult stem cell-derived organoids.
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- It exclusively supports XMR transactions, ensuring that all payments remain private and untraceable.
- We then identified 311 opioid keywords and jargons to recognize 28,106 listings and 13,508 forum traces related to underground opioid trading activities.
- Additionally, the growing prevalence of these cancers among the aging population is expected to boost demand for advanced therapeutics.
- A steering committee made up of senior executives from both organizations will oversee the execution of the new development hub.
- The Asia-Pacific region is projected to register the fastest growth, propelled by rapid industrialization, expanding manufacturing capacity, urban development, and increasing uptake of cost-effective technologies across China, India, and Southeast Asian economies.
- This port, coupled with the use of both Tor and clearnet mirrors, significantly increased the attack surface for adversaries.
Secure escrow system holds funds for 7-21 days depending on productcategory, with automatic release upon delivery confirmation or disputeresolution through our moderation team. All communications and sensitive data are protected using Pretty GoodPrivacy (PGP) encryption with 4096-bit keys, ensuring complete privacy fromthird-party interception. Select the active mirror above and copy the .onion URL to your clipboard. This onion is protected by custom sophisticated CAPTCHA systems and POWenabled to give you the best experience using DrugHub market.
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Public documentation revealed the use of port 5222, a choice that, while functional, is fraught with risks. This port, coupled with the use of both Tor and clearnet mirrors, significantly increased the attack surface for adversaries. The possibility of intercepting user data became more than a theoretical risk—it was a plausible scenario that could compromise both buyers and vendors alike. For example, there might be varying types of heroin or fentanyl, but we could not subcategorize them due to the lack of precise ontology. Addressing this challenge requires deep domain knowledge and expertise, which is constantly evolving. Another limitation is pointed out in the paper that multiple online suppliers might belong to the same vendor.
Configure your Jabber client with provided credentials to receive instant alerts. Private mirrors are displayed in your account dashboard after qualification. Europol said that 288 suspects were arrested and more than 50.8 million euros ($53.4 million) in cash and virtual currencies, 850 kilograms of drugs and 117 firearms were seized in a series of raids in several countries. The facilities, which the province is calling HART hubs, are part of the Progressive Conservative government’s marked shift away from harm reduction policies and toward a focus on addictions treatment and recovery. Novartis broke ground on a 700,000-square-foot flagship manufacturing hub in December.
New vendors without an existing darknet marketplace history can join Drughub Market by paying a $1000 securitydeposit. This deposit reinforces trust on the Drughub darknet, ensures a commitment to high-qualityservice, and acts as insurance against potential disputes. Access Drughub market onion links or official Drughub mirrors to get started today. As observed in our data set, the opioid suppliers in the marketplaces Evolution, Pandora, and Silk Road accepted escrow as a method of payment. In fact, the shutdown of the marketplace Evolution was discovered to be an exit scam, with the site’s operators shutting down abruptly to steal the approximately US $12 million in bitcoins that it was holding as an escrow [39]. Inspired by the work [36] investigating the supplier migration phenomenon between underground marketplaces, we also evaluated the migrant suppliers who, for the first time, began to trade in a new market, m’, after the closure of marketplace m.
HUB meticulously crafts its targeted marketing campaigns to highlight specific applications of organoid technology to accelerate and improve drug testing. The company’s proactive approach to using digital platforms for outreach has played a crucial role in demystifying complex scientific processes and showcasing the tangible benefits of organoids in drug discovery and development. This award recognizes HUB at the forefront of innovation and growth in the field of organoid technology, continuously improving its offerings to meet the dynamic needs of drug developers and providing state-of-the-arts solutions.
Infrastructure development, manufacturing expansion, and technology adoption offer strong opportunities. When you donate to CovertAction Magazine, you are supporting investigative journalism. Your contributions go directly to supporting the development, production, editing, and dissemination of the Magazine. As time passed, the men from Delta Force adopted a mercenary attitude about military service, which accounted in part for their ever-worsening behavior.
Paste the mirror URL in Tor browser, complete CAPTCHA verification, andcreate your secure account. If canary is not updated or signature fails verification, assume compromise. Admin key is used for signing official announcements, canary files, and critical security notices.
When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis. Although a large body of current research is focused on pathways for treatment of opioid use disorder and analyzing deaths per treatment capacity of substance use providers, these research areas are limited to the demand side of the opioid epidemic [40,41]. We believe that the findings and pattern analyses presented here, which place concentration on the supply side, might suggest a new direction to focus and will serve as a useful complement to current research conducted within the domain of addiction medicine. This section elaborates on the methodology used to identify opioid trading information in the anonymous market and forums. Specifically, we collected approximately 248,359 unique listings and 1,138,961 unique forum traces (ie, threads of posts) from 10 anonymous online marketplaces and 6 forums. We then identified 311 opioid keywords and jargons to recognize 28,106 listings and 13,508 forum traces related to underground opioid trading activities.
It exclusively supports XMR transactions, ensuring that all payments remain private and untraceable. The platform is built with robust security features, including anti-DDOS and anti-phishing measures, making it one of the most secure marketplaces on the Tor network. By exclusively accepting Monero (XMR) for all transactions, the platform prioritizes anonymity and security for its users. Since its launch, DrugHub has become a go-to choice for those seeking a reliable and private marketplace on the dark web.
Enhanced account security through mandatory 2FA implementation usingtime-based one-time passwords (TOTP), preventing unauthorized access even ifcredentials are compromised. In case of marketplace downtime or critical issues preventing normal support access, check this clearnet website for announcements. We will post updates regarding extended downtime, security incidents, or migration notices. It is a priority for CBC to create products that are accessible to all in Canada including people with visual, hearing, motor and cognitive challenges. Jones has repeatedly rejected the suggestion that drug users could die as a result of a shift toward an abstinence-based treatment model. That same report concluded the health ministry did not provide a thorough, evidence-based business case for the hub model and did not provide proper impact analysis or do proper consultations with all affected people.
Anonymous online marketplaces are usually platforms for sellers and buyers to conduct transactions in a virtual environment. They usually come with anonymous forums for sellers and buyers to share information, promote their products, leave feedback, and share experiences about purchases. To understand how it works, we describe an opioid transaction’s operational steps on the anonymous online marketplaces and forums.
Finally, we used natural language processing techniques to extract opioid trading information to characterize underground opioid commodities, suppliers, and transactions. Our research collected product listings and forum posts from 10 anonymous online market places and 6 forums. Our study determined the underground marketplace and forum list based on darknet site search engines and previous research works [20]. More specifically, we used darknet site search engines (such as Recon, Darknet live, Dark Eye, dark.fail, and DNStats [21,22]) to search underground marketplaces and forums and then manually validated their activeness. In our study, we only selected marketplaces with more than 30 opioid listings. In this way, we gathered 5 active underground marketplaces with opioid listings.
Slated to open in by 2028, the project includes a new facility in Morrisville and a new site in Durham, as well as expansion of an existing Novartis facility in Durham. From a seemingly innocuous logo to systemic vulnerabilities, DrugHub’s downfall is a testament to the importance of vigilance in the digital age. It is a story that blends technical intrigue with the high stakes of the darknet, offering a glimpse into a world where even the smallest mistake can have monumental consequences. For now, the fate of DrugHub hangs in the balance, a stark reminder that even in the shadows, the light of scrutiny can find a way in.
